Handan Yavuz

Date of Birth : 23.06.1975
Place of Birth : Kayseri, Turkey
Gender : Female
Nationality : Turkish
Marital Status : Single
Foreign Language : English

BSc Chemistry Department, Hacettepe University, Ankara, 1992-1997
MSc Chemistry Department, Biochemistry Div., Hacettepe University, Ankara, 1997-1999
PhD Chemistry Department, Biochemistry Div., Hacettepe University, Ankara, 1999-2003

1998-... Research Assistance in Hacettepe University, Chemistry Department
11/2004-03/2005 Guest reseacher; Department of Biotechnology, Lund University, Lund, Sweden

A. Books

Denizli, A., Denkbaş, E.B., Yavuz, H., Akgöl, S., Odabaşı, M., Garipcan, B., Özkara, S., Biochemistry Laboratory, Hacettepe University, Faculty of Science, Department of Chemistry, Beytepe, Ankara, 2000.

B. Reports and Thesis

Yavuz H., Iron(III) Chelating Sorbents, Thesis of Master of Science, Hacettepe University, Ankara, 1999 (Advisor: Prof. Dr. Adil Denizli).
Yavuz H., Preparation of Immunoaffinity Microbeads for Removal of Cholesterol from Hypercholesterolemic Human Plasma, PhD Thesis, Hacettepe University, Ankara, 2003 (Advisor: Prof. Dr. Adil Denizli).

C. Papers (in Science Citation Index)


1. Denizli, A., Köktürk, G., Yavuz, H., Pişkin, E., Albumin Adsorption from Aqueous Solutions and Human Plasma in a Packed-Bed Column with Cibacron Blue F3GA-Zn(II) Attached Poly(EGDMA-HEMA) Microbeads, Reactive & Functional Polymers, 40 (3) 195-203, 1999.
2. Denizli, A.,Köktürk G., Yavuz, H., Pişkin, E., Dye Ligand Column Chromatography: Albumin Adsorption from Aqueous Media and Human Plasma with Poly(EGDMA-HEMA) Microbeads, J. Applied Polymer Science, 74, 2803-2810, 1999.


3. Denizli, A., Yavuz, H., Garipcan, B., Arıca, M.Y., Non-porous Monosize Polymeric Sorbents: Dye and Metal Chelate Affinity Separation of Lysozyme, Journal of Applied Polymer Science, 76(2) 115-124, 2000.
4. Denizli, A., Yavuz, H., Arıca, Y., Monosize and Non-Porous p(HEMA-co-MMA) Microparticles Designed as Dye- and Metal-Chelate Affinity Sorbents, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 174(3) 307-317,2000.
5. Kassab, A., Yavuz, H., Odabaşı, M., Denizli, A.,Human Serum Albumin Chromatography by Cibacron Blue F3GA-Derived Microporous Polyamide Hollow Fibre Affinity Membranes, Journal of Chromatography Biomedical Applications, 746(2) 123, 2000.
6. Arıca, M.Y., Yavuz, H., Patır, S., Denizli, A.,Immobilization of Glucoamylase onto Spacer-Arm Attached Magnetic Poly(methylmethacrylate) Microspheres: Characterization and Application to a Continuous Flow Reactor, Journal of Molecular Catalysis B: Enzymatic, 11, 127-138, 2000.


7. Arıca, M.Y., Yavuz, H., Denizli, A.,Immobilization of Glucoamylase on the Plain and on the Spacer Arm Attached Poly(HEMA-EGDMA) Microspheres,Journal of Applied Polymer Science, 81, 2702-2710, 2001.
8. Yavuz, H., Arıca, Y., Denizli, A.,Therapeutic Affinity Adsorption of Iron(III) with Dye and Ferritin Immobilized PHEMA Adsorbent, Journal of Applied Polymer Science,82, 186-194, 2001.
9. Akgöl, S., Kaçar, Y., Özkara, S., Yavuz, H., Denizli, A.,Arıca, M.Y., Immobilization of Catalase via Adsorption onto L-Histidine Grafted Functional PHEMA Based Membrane, Journal of Molecular Catalysis B: Enzymatic, 15, 2001, 197-206.


10. Şenel, S., Denizli, F., Yavuz, H., Denizli, A.,Bilirubin Removal from Human Plasma by Dye Affinity Microporous Hollow Fibers, Separation Science and Technology,37(8) 1989-2006, 2002.
11. Yavuz, H., Patır, S., Say, R., Kaçar, Y., Arıca, Y., Denizli, A.,Affinity Separation of Plasma Proteins using a Newly Synthesized Methacrylamidoalanine Incorporated Porous pHEMA Membranes, Separation Science and Technology, 37 (9) 2077-2095, 2002.
12. Özkara, S., Yavuz, H., Patır, S., Arıca, M.Y., Denizli, A.,Separation of Human-Immunoglobulin-G with L-histidine Immobilised Pseudo-specific Bioaffinity Adsorbents, Separation Science and Technology, 37(3) 717-731, 2002.
13. Yavuz, H., Kaçar, Y., Denizli, A., Arıca, M.Y., Congo Red Attached Monosize Poly(HEMA-co-MMA) Microspheres for Use in Reversible Enzyme Immobilization, Biochemical Engineering Journal, 10, 1-8, 2002.


14. Yavuz, H., Duru, E., Genç, Ö., Denizli, A., Cibacron Blue F3GA incorporated poly(methylmethacrylate) beads for albumin adsorption in batch system, Colloids and Surfaces A: Physicochem. Eng. Aspects, 223, 185, 2003.

Denizli, A., Yavuz, H., Arpa, Ç., Bektas, S., Genç, Ö., Cysteinylhexapeptide Attached Poly(2-Hydroxyethyl Methacrylate) Beads for Cd(II) Removal from Human Plasma in a Packed-Bed Column, Separation Science and Technology,38 (8) 1869-1881, 2003.
Akgöl, S., Yavuz, H., Şenel, S., Denizli, A., Glucose Oxidase and Catalase Adsorption onto Cibacron Blue F3GA-Attached Microporous Poyamide Hollow Fibers, Reactive and Functional Polymers, 55 (2003) 45-51.
Yavuz, H., Denizli, A., Immunoaffinity beads for selective removal of cholesterol from human plasma, Journal of Biomaterials Science Polymer Edition, 14 (5) 395, 2003.
Ozkara, S., Yavuz, H., Denizli, A., Purification of immunoglobulin G from Human plasma by metal-chelate affinity chromatography, Journal of Applied Polymer Science, 89, 1567, 2003.
Rad, A.Y., Yavuz, H., Kocakulak, M., Denizli, A., Bilirubin removal from human plasma with albumin immobilized magnetic poly(2-hydroxyethyl methacrylate) beads, Macromolecular Bioscience, 3, 471, 2003.


Yavuz, H., Denizli, A., Dye affinity hollow fibers for albumin purification, Macromolecular Bioscience, 4 (2), 84, 2004.
Emir, S., Say, R., Yavuz, H., Denizli, A., A new metal chelate affinity adsorbent for Cytochrome c, Biotechnology Progress, 20, 223, 2004.
Karakoç, V., Yavuz, H., Denizli, A., “Affinity adsorption of recombinant human interferon-α on a porous dye-affinity adsorbent”, Colloids and Surfaces A: Physicochemical Engineering Aspects, 240, 93-99, 2004.
Yavuz, H., Akgöl, S., Arıca, Y., Denizli, A., Concanavalin A Immobilized Affinity Adsorbents for Reversible Use in Yeast Invertase Adsorption, Macromolecular Bioscience, 4, 674-679, 2004.
Uzun, L., Yavuz, H., Say, R., Ersöz, A., Denizli, A.,Poly(ethylene glycol dimethacryl- ate-glycidyl methacrylate) Monolith as a Stationary Phase in Dye-Affinity Chromatography, Industrial and Engineering Chemistry Research, 43, 6507-6513,2004.
Yavuz, H., Say, R., Andaç, M., Bayraktar, N., Denizli, A., Performance of Dye-Affinity Beads for Aluminium Removal in Magnetically Stabilized Fluidized Bed, Biomagnetic Research and Technology, 2:5, 2004.


Kara, A., Osman, B., Yavuz, H., Beşirli, N., Denizli, A.,Immobilization of a-Amylase on Cu2+ Chelated Poly(ethylene glycol dimethacrylate-n-vinyl imidazole) Matrix via Adsorption, Reactive and Functional Polymers, 62, 1, 61-68,2005.
Yavuz, H., Denizli, A.,Immunoadsorption of Cholesterol on Protein A Oriented Beads, Macromolecular Bioscience, 5, 39-48,2005.
Yavuz, H., Odabaşı, H., Akgöl, S., Denizli, A.,Immobilized Metal Affinity Polymeric Beads for Ferritin Adsorption, Journal of Biomaterials Science Polymer Edition,16, 5, 673-684, 2005.
Bereli, N., Akgöl, S., Yavuz, H., Kocakulak, M., Denizli, A.,Antibody Purification by Concanavalin A Affinity Chromatography, Journal of Applied Polymer Science,97, 1202-1208, 2005.
Yavuz, H., Say, R., Denizli, A., Iron Removal from Human Plasma Based on Molecular Recognition using Imprinted Beads, Materials Science and Engineering C, 25, 4, 521-528,2005.


Altıntaş, E.B., Yavuz, H., Say, R., Denizli, A., Methacryloylamidoglutamic acid having porous magnetic beads as a stationary phase in metal chelate affinity chromatography, Journal of Biomaterials Science Polymer Edition, Vol 17, No 1-2, 213-226, 2006.
Bereli, N., Uzun, L., Yavuz, H., Elkak, A., Denizli, A:, Antibody Purification Using Porous Metal-Chelated Monolithic Columns, Journal of Applied Polymer Science, 101 (1) 395-404, 2006.
Türkmen, D., Yavuz, H., Denizli, A., Synthesis of tentacle type magnetic beads as immoblized metal chelate affinity support for cytochrome c adsortion, International Journal of Biological Macromolecules, 28, 126-133, 2006.
Babac, C., Yavuz, H., Galaev, I.Y., Pişkin, E., Denizli, A., Binding of antibodies to concanavalin A-modified monolithic cryogel, Reactive and Functional Polymers, 66, 1263-1271, 2006.
Yavuz, H., Andaç, M., Uzun, L., Say, R., Denizli, A., Molecular recognition based iron removal from human plasma with imprinted membranes, The International Journal of Artificial Organs, 29, 9, 591-595, 2006.
Keçili, R., Say, R., Yavuz, H., Synthesis and characterization of pseudo-affinity ligand for penicilin acylase purification, International Journal of Biological Macromolecules, 39, 4-5, 250-255, 2006.
Yavuz, H., Akgöl, S., Say, R., Denizli, A.,Affinity Separation of Immunoglobulin G Subclasses on Dye Attached Poly(hydroxypropyl methacrylate) Beads, International Journal of Biological Macromolecules, 39, 303-309, 2006.
Yavuz, H., Denizli, A., Güngüneş, H., Safarikova, M., Safarik, I., Biosorption of mercury on magnetically modified yeast cells, Separation and Purification Technology, 52, 253-260, 2006.
Yavuz, H., Pişkin, K., Denizli, A., Concanavalin A Conjugated Affinity Beads for Cell Affinity Chromatography, Reactive and Functional Polymers (submitted).

Polymer Technology: Production of polymers having different bulk and surface properties and their medical and biological applications.
Biochemistry: Hemoperfusion- Removal of toxic substances (bilirubin, pathogenic antibodies, cholesterol, metal ions such as iron and cadmium etc.) from human plasma. Enzyme immobilisation.
Chromatographic Techniques: Preparation of polymeric biospecific sorbents and their use for the purification of enzymes and proteins (Bioaffinity Chromatography, Dye Affinity Chromatography, Immobilised Metal Affinity Chromatography)
Biomaterials: Production of polymeric biomaterials, characterisation of bulk and surface properties. Modification of their surfaces by various methods.

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