News
Tuesday, December 16, 2014
New Paper in RSC Advances, Issue 59, 2014
Affinity-recognition-based polymeric cryogels for protein depletion studies
Several affinity-recognition-based polymeric materials have been developed to aid the depletion of highly abundant proteins in serum samples. Among these, cryogels with macroporous structures may be useful in the field of protein depletion. In particular, the requirement to deplete highly abundant proteins prior to proteome investigations makes cryogels attractive for researchers. In the present review, recent developments and applications of affinity-recognition-based polymeric materials and cryogels are reviewed regarding protein depletion.
Tuesday, December 16, 2014
New Paper in RSC Advances, Issue 59, 2014
Affinity-recognition-based polymeric cryogels for protein depletion studies
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Tuesday, December 16, 2014
AFFTECH 2015 and NANOMED 2015
9th National Affinity Techniques Symposium and 4th Nanomedicine World Congress
It is our great pleasure to invite you to participate in the “9th National Affinity Techniques Symposium” (AFFTECH 2015) and “4th Nanomedicine World Congress (NANOMED 2015)” that will be organize following each other between 6-12 September 2015, to be held in Koycegiz, Mugla, Turkey. The meetings will bring together experts and scientists from academia, industry, and also those involved in funding regulatory and commercial enterprises in this multidisciplinary field, from all disciplines including fundamental sciences, engineering and health sciences and related technologies. The sessions will include keynote and invited lectures on affinity technologies/nanomedicine in an interdisciplinary manner covering different fields of applications. Thematically-related research and development addressing significant problems, current developments, planned research directions and challenges will be presented by leading researchers. There will be also oral, short oral and poster presentations selected from the abstracts to be submitted. Best presentations will also be awarded. ...
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Tuesday, December 16, 2014
AFFTECH 2015 and NANOMED 2015
9th National Affinity Techniques Symposium and 4th Nanomedicine World Congress
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Tuesday, December 9, 2014
Nanoteknoloji ve Nanosensörler Semineri
Kimya derslerinde öğrencilerimizin bilinçlenmesi amacı ile okulumuzda 9 Aralık 2014 günü bir seminer düzenlendik. Seminer katılımcımız Hacettepe Üniversitesi Fen Fakültesi Kimya Bölümü Biyokimya Anabilim Dalı Başkanı Prof.Dr. Adil DENİZLİ “Nanoteknoloji ve Nanosensörler“konulu sunumunu gerçekleştirdi.
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Tuesday, December 9, 2014
New Paper in RSC Analyst
Novel tentacle-type polymer stationary phase grafted with anion exchange polymer chains for open tubular CEC of nucleosides and proteins
Cemil Aydoğan, Kemal Çetin and Adil Denizli
A novel and simple method for preparation of a tentacle-type polymer stationary phase grafted with polyethyleneimine (PEI) anion exchanger was developed for open tubular capillary electrochromatography (OT-CEC) of nucleosides and proteins. The polymeric stationary phase was prepared using 3-chloro-2-hydroxypropyl methacrylate (HPMA-Cl)-based reactive monomer. The preparation procedure included pretreatment of the capillary inner wall, silanization, in situ graft polymerization with HPMA-Cl and PEI modification. To compare with the tentacle-type capillary column with PEI functionalization, a monolayer capillary column without PEI functionalization was also prepared. The electrochromatographic characterization of the prepared open tubular column was performed using alkylbenzenes. [...]
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New Paper in RSC Analyst
Novel tentacle-type polymer stationary phase grafted with anion exchange polymer chains for open tubular CEC of nucleosides and proteins
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Tuesday, December 9, 2014
New Paper in ACS Analytical Chemistry
Lysine-Promoted Colorimetric Response of Gold Nanoparticles: A Simple Assay for Ultrasensitive Mercury(II) Detection
Gulsu Sener, Lokman Uzun, Adil Denizli
Although numerous methods have been reported for the analysis of toxic mercury (Hg2+) ions in drinking water, development of simple, rapid, inexpensive, and sensitive sensors still remains a great challenge. Here, we report a simple yet very sensitive colorimetric assay for rapid detection of Hg2+ in water. The colorimetric assay is based on the aggregation of as-prepared citrate-capped gold nanoparticles (AuNPs) in the presence of Hg2+ ions and the positively charged amino acid, lysine. The detection limit of this inexpensive colorimetric assay is 2.9 nM, which is below the limit value (10 nM) defined by the U.S. Environmental Protection Agency in drinkable water. Also, the colorimetric response of citrate-capped AuNPs in the presence of lysine is very selective to the Hg2+. In addition, the colorimetric assay is very fast, and all analyses can be completed within a few minutes.
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New Paper in ACS Analytical Chemistry
Lysine-Promoted Colorimetric Response of Gold Nanoparticles: A Simple Assay for Ultrasensitive Mercury(II) Detection
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Tuesday, December 9, 2014
New Paper in ACS Applied Materials & Interfaces
Colorimetric Sensor Array Based on Gold Nanoparticles and Amino Acids for Identification of Toxic Metal Ions in Water
Gulsu Sener, Lokman Uzun, Adil Denizli
A facile colorimetric sensor array for detection of multiple toxic heavy metal ions (Hg(2+), Cd(2+), Fe(3+), Pb(2+), Al(3+), Cu(2+), and Cr(3+)) in water is demonstrated using 11-mercaptoundecanoic acid (MUA)-capped gold nanoparticles (AuNPs) and five amino acids (lysine, cysteine, histidine, tyrosine, and arginine). The presence of amino acids (which have functional groups that can form complexes with metal ions and MUA) regulates the aggregation of MUA-capped particles; it can either enhance or diminish the particle aggregation. The combinatorial colorimetric response of all channels of the sensor array (i.e., color change in each of AuNP and amino acid couples) enables naked-eye discrimination of all of the metal ions tested in this study with excellent selectivity.
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